Live monitoring of dynamic cell behaviour opens a whole new world of potential discoveries in cell biology.

Today’s stem cell scientists are facing an ongoing dilemma: Every experiment could bring fundamental breakthroughs, but certain assays can also seriously damage – or even kill – the cells. Dr. Mathieu Frechin, Head of Quantitative Biology at Nanolive SA describes the risk. “Putting your cells under a light sheet microscope, which is currently considered the gold standard, is like putting your cells under the sun at noon at the equator. They get sunburned,” says Frechin. In fact, one of the biggest challenges in modern stem cell biology is live-cell imaging in 3D to understand the role of stem cells in tissue maintenance and repair (Park et al., 2016).

Holotomography: a new technique for exploring the insides of living cells

Read more about how this new technology is helping stem cell researchers to gain valuable insights.